1 | © 2025 Journey Medical Corporation. All rights reserved.
INVESTOR PRESENTATION
July 2025
PRESENTED BY:
Claude Maraoui
Co-Founder, President and CEO
Joseph Benesch
Chief Financial Officer
Ramsey Alloush
Chief Operating Officer
2 | © 2025 Journey Medical Corporation. All rights reserved.
FORWARD-LOOKING STATEMENTS
FORWARD-LOOKING STATEMENTS
This press release may contain “forward-looking statements” within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended. As used below and throughout this press
release, the words “the Company”, “we”, “us” and “our” may refer to Journey Medical. Such statements include, but are not limited to, any statements relating to our growth strategy and product development programs and any other statements that
are not historical facts. The words “anticipate,” “believe,” “estimate,” “may,” “expect,” “will,” “could,” “project,” “intend” and similar expressions are generally intended to identify forward-looking statements. Forward-looking statements are based on
management’s current expectations and are subject to risks and uncertainties that could negatively affect our business, operating results, financial condition and stock price. Factors that could cause actual results to differ materially from those currently
anticipated include: the fact that our products and product candidates are subject to time and cost intensive regulation and clinical testing and as a result, may never be successfully developed or commercialized; a substantial portion of our sales derive
from products that may become subject to third-party generic competition, the introduction of new competitor products, or an increase in market share of existing competitor products, any of which could have a significant adverse impact on our
operating income; we operate in a heavily regulated industry, and we cannot predict the impact that any future legislation or administrative or executive action may have on our operations; our revenue is dependent mainly upon sales of our
dermatology products and any setback relating to the sale of such products could impair our operating results; competition could limit our products’ commercial opportunity and profitability, including competition from manufacturers of generic versions
of our products; the risk that our products do not achieve broad market acceptance, including by government and third-party payors; our reliance third parties for several aspects of our operations; our dependence on our ability to identify, develop, and
acquire or in-license products and integrate them into our operations, at which we may be unsuccessful; the dependence of the success of our business, including our ability to finance our company and generate additional revenue, on the successful
commercialization of our recently approved product, Emrosi , and any future product candidates that we may develop, in-license or acquire; clinical drug development is very expensive, time consuming, and uncertain and our clinical trials may fail to
adequately demonstrate the safety and efficacy of our current or any future product candidates; our competitors could develop and commercialize products similar or identical to ours; risks related to the protection of our intellectual property and our
potential inability to maintain sufficient patent protection for our technology and products; our business and operations would suffer in the event of computer system failures, cyber-attacks, or deficiencies in our or our third parties’ cybersecurity; the
substantial doubt about our ability to continue as a going concern; the effects of major public health issues, epidemics or pandemics on our product revenues and any future clinical trials; our potential need to raise additional capital; Fortress controls a
voting majority of our common stock, which could be detrimental to our other shareholders; as well as other risks described in Part I, Item 1A, “Risk Factors,” in our Annual Report on Form 10-K for the year ended December 31, 2024, subsequent
Reports on Form 10-Q, and our other filings we make with the SEC. We expressly disclaim any obligation or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in our
expectations or any changes in events, conditions or circumstances on which any such statement is based, except as may be required by law, and we claim the protection of the safe harbor for forward-looking statements contained in the Private
Securities Litigation Reform Act of 1995.
TRADEMARKS
This confidential presentation may contain trademarks, service marks, trade names and copyrights of other companies, which are the property of their respective owners. Solely for convenience, some of the trademarks, service marks, trade names and
copyrights referred to in this presentation may be listed without the TM, SM, © or ® symbols, but the Company will assert, to the fullest extent under applicable law, the rights of the applicable owners, if any, to these trademarks, service marks, trade
names and copyrights.
MARKET & INDUSTRY DATA
Projections, estimates, industry data and information contained in this presentation, including the size of and growth in key end markets, are based on information from third-party sources and management estimates. Although the Company believes that
its third party-sources are reliable, the Company cannot guarantee the accuracy or completeness of its sources. The Company's management estimates are derived from third-party sources, publicly available information, the Company's knowledge of its
industry and assumptions based on such information and knowledge. The Company's management estimates have not been verified by any independent source. All of the projections, estimates, market data and industry information used in this
presentation involve a number of assumptions and limitations, and you are cautioned not to give undue weight to such information. In addition, projections, estimates and assumptions relating to the Company's and its industry's future performance are
necessarily subject to a high degree of uncertainty and risk due to a variety of factors, including, but not limited to, those described above, that could cause future performance to differ materially from the Company's expressed projections, estimates and
assumptions or those provided by third parties.
3 | © 2025 Journey Medical Corporation. All rights reserved.
NASDAQ: DERM
Market Cap: $167.3MM
*
Shares Outstanding: 23.3MM
*
ADTV (last 90-days): 133K
*
*Market data as of 6/30/2025
4 | © 2025 Journey Medical Corporation. All rights reserved.
INVESTMENT HIGHLIGHTS
1. Source: Symphony Health
Commercial-stage pharmaceutical company focused on proprietary & patented products serving prescription dermatology
markets with a total market size of ~$5.8 billion
1
(acne, rosacea, hyperhidrosis)
Key growth driver: EMROSI launched April 2025 in U.S. with head-to-head superiority over market leader (Oracea
®
);
Potential to drive significant revenue growth and earnings leverage going forward
Core dermatology product portfolio contribution-positive with 2024 revenues of $55 million
Successful business development efforts to date out-licensing international rights to current products and
in-licensing new assets to leverage Journey’s U.S. commercial & development infrastructure
Solid balance sheet with $21.1MM in cash as of 3/31/2025; Cash balance increased from Q4 ($20.3M)
DERM stock added to the Russell 2000 & 3000 indexes on June 27, 2025; Increased daily volume / liquidity
Multiple catalysts & milestones to drive value
5 | © 2025 Journey Medical Corporation. All rights reserved.
Note: Bausch Health Companies, Inc. was formerly known as Valeant Pharmaceuticals International
Claude Maraoui
Founder, President
& Chief Executive Officer
30+ years of
experience
commercializing
successful dermatology
products
Ramsey Alloush
Chief Operating Officer
15+ years of
experience
advising pharmaceutical
companies
Robert Nevin
Chief Commercial Officer
24+ years of
experience
in pharmaceutical,
lab and medical
management
Andrew Zwible
Vice President,
Operations
10+ years of
experience
in dermatology
pharmaceuticals
Jessica Yeaman
National Sales Director
17+ years of
experience
in dermatology
pharmaceuticals
Ernest Galvan
Vice President,
Business Development
26+ years of
experience
in dermatology
pharmaceuticals
Joseph Benesch
Chief Financial Officer
25+ years of
experience
in public and private
pharmaceutical
companies
SENIOR MANAGEMENT WITH SIGNIFICANT DERMATOLOGY EXPERIENCE
Srinivas
Sidgiddi, M.D.
Vice President,
Research & Development
18+ years of
experience
in pharmaceutical
development and
clinical research
6 | © 2025 Journey Medical Corporation. All rights reserved.
OUR LEADERS HAVE LAUNCHED MANY SUCCESSFUL DERMATOLOGY BRANDS
Experience growing & managing marquee medical dermatology brands that generated over $2B in sales
1
:
A majority of our management team and sales force were part of the commercial organization at Medicis
(which was sold to Bausch Health Companies Inc., for approximately $2.5B in 2012)
1. Per Symphony Health based on peak sales
Built and launched new brands in the marketplace
Managed product life cycles to extend revenue streams
Created innovative, first-in-class growth strategies
7 | © 2025 Journey Medical Corporation. All rights reserved.
HIGHLIGHTS & SALES EXPERIENCE
OUR COMMERCIAL ORGANIZATION IS HIGHLIGHTED BY A UNIQUE AND
EXPERIENCED DERMATOLOGY SALES FORCE
Sales representatives have deep-rooted customer relationships
in their respective territories.
Our sales reps are incentivized to build their own “business”:
We screen for individuals with an entrepreneurial and self-starter mindset
We incentivize performance through our unique incentive program
We provide equity rewards to incentivize performance
COVERAGE IN THE
U.S. DERMATOLOGY
TRx MARKET
70%
COVERAGE IN
THE TOP 50
U.S. MSAs
80%
DERMATOLOGY
SALES TERRITORIES
35
10 yrs.
Avg. Dermatology
Sales Experience
305 yrs.
Combined Experience
in Dermatology
98
Regional Sales
Awards
12
Sales Rookies
of the Year
72
President’s Club
Trophies
8 | © 2025 Journey Medical Corporation. All rights reserved.
PRIOR TO THE LAUNCH OF EMROSI , THE CORE PRODUCT PORTFOLIO
ACCOUNTED FOR 90% OF PRODUCT SALES
1. Symphony Health (all specialties data). TRx = Total number of prescriptions
2. International Hyperhidrosis Society,
3. Dolittle, et al, 2016, Hyperhidrosis: an update on prevalence and severity in the United States, Archives of Dermatology Research
4. Wehausen, B., Hill, D. E, & Feldman, S. R. (2016). Most people with psoriasis or rosacea are not being treated: a large population study. Dermatology Online Journal, 22(7).
Glycopyrronium 2.4% cloth for topical treatment of
primary axillary hyperhidrosis
43% prescription growth since acquiring the product
in Q2 2021
Addressable market of ~10M patients in the U.S.
2,3
Treatment of inflammatory lesions of non-nodular moderate to severe
acne vulgaris
The first and only FDA-approved topical formulation of minocycline
for acne
>23.7M topical acne RXs in 2024, category is highly promotion sensitive
1
Isotretinoin capsule for the treatment of severe
recalcitrant nodular acne
The oral isotretinoin market had over 2 million
prescriptions in 2023
1
Accutane TRx had compounded annual growth
of 42.8% from 2021 2024
Treatment of inflammatory lesions of rosacea
>4.3M topical rosacea RXs per year in 2024
1
An estimated 5% of Americans (~17M people) suffer from rosacea
4
Launched on April 7, 2025
9 | © 2025 Journey Medical Corporation. All rights reserved.
Mar-21 Apr-21 May-21 Jun-21
JOURNEY SUCCESSFULLY RELAUNCHED QBREXZA IN 3 MONTHS & INCREASED
PRESCRIPTIONS BY 43% IN 3 YEARS WITH LIMITED ADVERTISING SPEND
1
QBREXZA®
29%
DRYSOL
69%
OTHER
2%
2024 Branded Topical A.H.H. Market
(Full Year TRx, All Specialties
1
)
1. Symphony Health (all specialties data) excluding prescriptions for OTC and clinical strength antiperspirants. TRx = Total number of prescriptions
2. Doolittle J, Walker P, Mills T, Thurston J. Hyperhidrosis: an update on prevalence and severity in the United States. Arch Dermatol Res. 2016
Dec;308(10):743-749. doi: 10.1007/s00403-016-1697-9. Epub 2016 Oct 15. PMID: 27744497; PMCID: PMC5099353.
March 31, 2021
Journey executes asset
purchase agreement with
Dermira for Qbrexza
Develop Rebate Program
Develop Promotional Campaign
Soft Launch Promotion
May 14, 2021
Transaction with
Dermira Closes
DETAILS:
Qbrexza is a novel drug with largely untapped
potential in a dermatology-focused market
Dermira spent $82.8M in patient advertising
during the 3 years they promoted Qbrexza.
Journey has grown TRx by over 43% in 3 years,
spending less than 3% of Dermira’s commercial
budget by leveraging our experienced sales force
and unique access program.
1
97,914
116,081
123,129
139,746
2021 2022 2023 2024
Qbrexza
®
TRx Trajectory
(All Specialties)
Journey Begins Full Promotion
- June 2021
Journey begins
promotion
June 2021
10 | © 2025 Journey Medical Corporation. All rights reserved.
Jul-20 Aug-20 Sep-20 Oct-20 Nov-20 Dec-20 Jan-21 Feb-21 Mar-21
JOURNEY ACHIEVED A SUCCESSFUL BRAND LAUNCH OF ACCUTANE
®
IN A HIGHLY COMPETITIVE MARKET
1. Symphony Health (all specialties data).
TRx = Total number of prescriptions
Please see additional Important Safety Information for Accutane below and the Medication Guide and
full Prescribing Information here for Boxed Warning, Contraindications, other important Warnings
and Precautions, Drug Interactions, Use in Specific Populations, and other Adverse Reactions.
Journey Begins Promotion
- April 2021
July 29, 2020
Journey acquires
rights to Accutane
$1MM Upfront
Sell Into
Pharmacies
Develop Rebate Program
Develop Promotional Campaign
Accutane ,
14%
Other
Isotretinoins
2024 Isotretinoin Market
(Full Year TRx, All Specialties
1
)
DETAILS:
Accutane is one of the most
well-known brands in dermatology
The oral isotretinoin market
had over 2.2M TRx in 2023
1
Expands Journey’s acne vertical
with limited investment by
leveraging our experienced
sales force and unique access
program.
107,448
222,853
281,999
313,024
2021 2022 2023 2024
Accutane
®
Franchise TRx Trajectory
1
(All Specialties)
Journey begins promotion
Apr. 2021
11 | © 2025 Journey Medical Corporation. All rights reserved.
U.S. Commercial Launch April 2025
Leveraging Journey Medical’s Dermatology-Focused
Commercial Platform & Business Development Strategy
12 | © 2025 Journey Medical Corporation. All rights reserved.
EMROSI: COMMERCIAL HIGHLIGHTS
1. Wehausen, B., Hill, D. E, & Feldman, S. R. (2016). Most people with psoriasis or rosacea are not being treated: a large population study. Dermatology Online Journal, 22(7).
2. Source: Symphony, PHAST Prescription data
Emrosi received FDA approval in November 2024; On time, first-cycle review
Superior to both placebo and market-leading oral rosacea treatment, Oracea
®
Emrosi has potential to become the standard of care
17 million Americans suffer from rosacea
1
Established dermatology-focused commercial organization covering
83% of oral rosacea prescriptions
2
Potential to generate significant sales and earnings leverage
Out-licensing opportunities to generate cash and future revenue
13 | © 2025 Journey Medical Corporation. All rights reserved.
EMROSI: POTENTIAL BEST-IN-CLASS TREATMENT FOR ROSACEA
Capsule Image For Illustrative Purposes Only
PRODUCT PROFILE
INDICATION
1
Treatment of inflammatory lesions (papules and pustules) of rosacea in adults
PRODUCT
DESCRIPTION
1
Minocycline 40mg extended-release capsule:
Once-daily (QD) oral dosing; 16-week treatment duration
Each capsule contains a proprietary blend of 10 mg immediate-release & 30 mg
extended-release minocycline beads for uniform drug release throughout the day
Head-to-head superiority over market leader Oracea
®
demonstrated in Phase 3 trials
Safety profile similar to placebo
PUBLICATION
Phase 3 Clinical Data Published in JAMA Dermatology
(March 2025)
PATENTS
Three U.S. Orange Book listed patents issued
(expected market exclusivity to 2039)
MARKET SIZE
Rosacea treatment sales in the U.S. were approximately $1.2B in 2024
2
Oracea
®
the market leader had $311M in sales in 2024
2
1. EMROSI. Prescribing Information. Journey Medical Corporation; 2024
2. Source: Symphony, PHAST Prescription data.
14 | © 2025 Journey Medical Corporation. All rights reserved.
EMROSI WAS FDA-APPROVED ON NOVEMBER 1, 2024
PHASE III (Complete)
First
Patient In
Top Line
Data
NDA
Acceptance
FDA
Approval
H1
H2 H1 H2 H1 H2
2022 2023 2024
Phase 3 Initiation March 14, 2022
Two multicenter active and placebo-controlled
studies in 320 patients with moderate to severe
Papulopustular Rosacea
Emrosi (N=120); Oracea (N=120); Placebo
(N=80)
48 U.S. investigator sites; 14 sites in Germany
Results Announced July 2023
PHASE II (Complete)
Safety & Efficacy
Study in 200
patients with
Papulopustular
Rosacea
(Germany)
PHASE I (Complete)
Systemic PK Study
(24 healthy subjects)
3 Arms Emrosi
(20 & 40 mg) & Oraycea
Bridging PK Study
(24 healthy subjects)
3 Arms Emrosi
(40 mg) Fasting & Fed and
Solodyn 105 mg Fasting
Sub-Antimicrobial Study
(60 healthy subjects)
Sub-Antimicrobial Study Results Announced June 13, 2023
Phase 3 Topline Results Announced
(July 11, 2023)
Successful completion
of Pre-NDA meeting
(December 6, 2023)
NDA Submission
(January 4, 2024)
FDA-Approval
(November 1, 2024)
15 | © 2025 Journey Medical Corporation. All rights reserved.
62.7
39
28.2
Emrosi
(40mg)
N=245
Oracea
(40mg)
N=246
Placebo
N=162
% of Subjects
Emrosi was statistically superior to
Oracea and placebo on all co-primary
and secondary endpoints in Phase 3
clinical trials.
IGA Success:
61% greater than Oracea and 122% greater than
placebo, calculated as a relative percentage
Inflammatory Lesion Reduction:
28% greater than Oracea and 68% greater
than placebo, calculated as a relative percentage
No other drugs have demonstrated
head-to-head superiority over Oracea
No significant safety issues noted
in these trials.
*All statistical tests were two-sided, with α=0.05 as level of significance
EMROSI DEMONSTRATED SUPERIOR EFFICACY OVER ORACEA
®
AND PLACEBO IN TWO PHASE 3 CLINICAL TRIALS
P<0.001
*
IGA Treatment Success - Week 16
1
(Pooled Data)
Inflammatory Lesion Absolute Change - Week 16
1
(Pooled Data)
P<0.001
*
-19
-14.8
-11.3
Emrosi
N=245
Oracea
N=246
Placebo
N=162
Lesion Count Change
P<0.001
*
P<0.001
*
PHASE 3
(Efficacy)
Note: *All statistical tests were two-sided, with α=0.05 as level of significance.
1. Data on file. Journey Medical Corporation
16 | © 2025 Journey Medical Corporation. All rights reserved.
27.9
12.5
Emrosi
N=245
Placebo
N=162
% of Subjects
EMROSI WAS SUCCESSFUL ON ALL SECONDARY ENDPOINTS
INCLUDING PERCENT CHANGE IN LESION COUNT
AND ERYTHEMA REDUCTION
*All statistical tests were two-sided, with α=0.05 as level of significance
P<0.001
*
Erythema Success - Week 16
1
(Pooled Data)
Inflammatory Lesion % Change - Week 16
1
(Pooled Data)
-76%
-61%
-46%
Emrosi
N=245
Oracea
N=246
Placebo
N=162
Lesion Count % Change
Inflammatory Lesion Percent Change:
Emrosi was statistically superior to Oracea
and placebo in reducing percent change in
inflammatory lesion count in the Phase 3 trials.
24% greater than Oracea and 65% greater
than placebo, calculated as a relative percentage
Erythema Success:
Emrosi was statistically superior to placebo in
reducing the Clinician’s Erythema Assessment
(CEA) score by at least 2 points from baseline
(Erythema Success) in the Phase 3 trials.
123% greater erythema success than placebo, calculated
as a relative percentage
P<0.001
*
P<0.001
*
PHASE 3
(Efficacy)
Note: *All statistical tests were two-sided, with α=0.05 as level of significance.
1. Data on file. Journey Medical Corporation
17 | © 2024 Journey Medical Corporation. All rights reserved.
EMROSI DEMONSTRATED ONSET OF EFFICACY
AS EARLY AS WEEK 2 COMPARED TO PLACEBO
Study design: Two identically designed, randomized,
double-blind, active- and placebo-controlled Phase 3 trials
(MVOR-1 and MVOR-2), including 653 total participants,
to compare the impact of oral EMROSI (minocycline
HCl 40 mg capsules), Oracea
®
(doxycycline, 40 mg), and
placebo in adults with moderate-to-severe rosacea. The
trial duration was 16 weeks, with patient assessments at
Weeks 2, 4, 8, 12 and 16.
*All statistical tests were two-sided, with α=0.05 as level
of significance.
NS=not significant.
Onset of Efficacy was an
exploratory endpoint in Emrosi’s
Phase 3 Trials
Emrosi’s efficacy vs. placebo was
significantly greater at each study
visit and across both endpoints.
PHASE 3
(Efficacy)
Note: *All statistical tests were two-sided, with α=0.05 as level of significance.
1. Data on file. Journey Medical Corporation
1 1
18 | © 2024 Journey Medical Corporation. All rights reserved.
PATIENT RESULTS AT BASELINE & 16 WEEKS
POST TREATMENT
Actual patient images from Emrosi Phase 3 Clinical Trials. Photos used with permission.
Results of individual patients may not be typical, as individual results may vary.
PHASE 3
(Efficacy)
19 | © 2024 Journey Medical Corporation. All rights reserved.
Actual patient images from Emrosi Phase 3 Clinical Trials. Photos used with permission.
Results of individual patients may not be typical, as individual results may vary.
PATIENT RESULTS AT BASELINE & 16 WEEKS POST
TREATMENT
PHASE 3
(Efficacy)
20 | © 2024 Journey Medical Corporation. All rights reserved.
EMROSI DEMONSTRATED A SIMILAR SAFETY PROFILE
TO PLACEBO
1,2
IN PHASE 3 STUDIES
1
Key Treatment-Related Adverse Events
(N=638)
2.1% 2.1%
1.6%
0.8%
0.0%
3.4%
2.1%
0.8%
1.3%
2.1%
2.5%
3.8%
0.0%
1.3% 1.3%
0%
2%
4%
6%
8%
10%
12%
14%
Headache Diarrhea Dyspepsia Gastroesophageal Reflux Nausea
% of Patients
Emrosi (Minocycline, 40mg)
(N=243)
Oracea® (Doxycycline, 40mg)
(N=237)
Placebo
(N=158)
The frequency of key treatment-related adverse events was low,
and most were reported as mild or moderate.
PHASE 3
(Safety)
1. Data on file. Journey Medical Corporation
21 | © 2025 Journey Medical Corporation. All rights reserved.
One publication and two manuscript submissions in process at leading peer-reviewed journals,
covering the following topics:
Safety & Efficacy vs. Placebo & Oracea for Lesions & Erythema (published in JAMA Dermatology; March 5, 2025)
Microbiology
Quality of Life Improvement
Clinical posters will communicate key aspects of the clinical data at major dermatology conferences:
PK Safety Study (Fall Clinical; Oct. 2023)
Sub-Antimicrobial Study (AAD; Mar. 2024)
QoL Improvement (DEF NP/PA; Jul. 2024)
Systemic vs. Dermal PK in Emrosi & Oracea (Fall Clinical; Oct. 2024)
QoL Improvement (Encore presentation at Winter Clinical; Feb. 2025)
Body Weight Analysis (SDPA Annual Summer Dermatology Conference; June 2025)
EMROSI PUBLICATION & DATA COMMUNICATION PLAN
22 | © 2025 Journey Medical Corporation. All rights reserved.
Dermatology Provider’s Perceptions of Emrosi
40%
of HCPs report a “very
high therapeutic
unmet need” in the
treatment of rosacea
70%
of HCPs perceive Emrosi
to be “Extremely
Valuable
74%
of HCPs are “Very
Likely” to prescribe
Emrosi
Based on independent quantitative market research with 50 dermatology-focused healthcare professionals (HCPs)
88%
of HCPs ranked Head-to-Head
superiority data over Oracea
®
as a top reason for prescribing
Emrosi
Additional Takeaways
HCPs are sensitive to patient out-of-pocket costs above $50 per month
HCPs are sensitive to payer restriction scenarios, such as prior authorization, step edits and medical necessity
MAJORITY OF HIGH PRESCRIBERS FOR ROSACEA SURVEYED BELIEVE EMROSI IS
“EXTREMELY VALUABLE” AND 74% STATED THEY ARE “VERY LIKELY” TO PRESCRIBE
23 | © 2024 Journey Medical Corporation. All rights reserved.
17,000,000
The U.S. Rosacea Market was
~$1.2bn in 2024
3
ORACEA
$311M in Sales
3
EMROSI HAS SUPERIOR EFFICACY TO THE MARKET LEADER ORACEA,
WHICH HAD 2024 SALES OF $311 MILLION
ESTIMATED U.S. ROSACEA PATIENTS
(2024)
It is estimated that ~5% of the
U.S. population (17mm people)
suffer from rosacea
2
STRATEGIC RATIONALE
Robust clinical data demonstrating
superior efficacy over Oracea with a
placebo-like safety profile
Efficacy is the primary driver for
physician adoption in oral rosacea
therapy
1
Complementary to Journey’s current
product mix and commercial footprint
Additional ex-U.S. out-licensing
opportunities (Excluding BRIC and CIS)
EMROSI SALES POTENTIAL IN
U.S. EXCEEDING $300mm
PEOPLE
1. Internal Market Research.
2. Wehausen, B., Hill, D. E, & Feldman, S. R. (2016). Most people with psoriasis or rosacea are not being treated: a large population study. Dermatology Online Journal, 22(7).
3. Symphony, PHAST Prescription data. TRx sales defined as TRx$ = TRx x WAC Price.
24 | © 2025 Journey Medical Corporation. All rights reserved.
Source: IQVIA Prescriber-level Data
TRx = Total number of prescriptions
94% of Oral Rosacea
TRx are written in
Dermatology
(based on IQVIA 2024 TRx)
83% of Oral Rosacea
Derm TRx will be
covered at launch
(based on IQVIA 2024 TRx)
JOURNEY MEDICAL’S SALES FORCE COVER THE VAST MAJORITY
OF ORAL ROSACEA PRESCRIPTIONS IN DERMATOLOGY
25 | © 2025 Journey Medical Corporation. All rights reserved.
EMROSI KEY TAKEAWAYS
EMROSI is the best-in-class oral therapy for inflammatory lesions of rosacea
and is expected to become the new standard of care in rosacea therapy
1. Head-to-head superiority over Oracea
®
demonstrated in two Phase 3 trials
2. Treatment results in as little as 2 weeks
3. Demonstrated placebo-like safety profile
4. Potential to achieve more than $300 million in global annual sales
5. Significant revenue and earnings potential given Journey’s existing
dermatology-focused commercial infrastructure
26 | © 2025 Journey Medical Corporation. All rights reserved.
U.S. Based Commercial Organization
Leverage proven commercial infrastructure
to launch acquired / developed products:
“Best in Dermatology sales and marketing organization
Network of 700+ specialty pharmacies
HCP-trusted access program provides coverage to more patients
Ex-U.S. Out-Licensing
Significant global out-licensing opportunity
for current and future products:
Leverage existing distributor relationships to out-license
current products in new geographies (e.g. $19M Maruho Transaction)
Dedicated BD function actively seeking new out-licensing opportunities
BUSINESS DEVELOPMENT STRATEGY
1. STRONG PORTFOLIO OF RX
DERMATOLOGY BRANDS
7 Commercial
Dermatology Assets
2. GROWTH THROUGH ACQUISITION & IN-LICENSING
Former Medicis management team experienced at
identifying undervalued assets
Products acquired since 2021 contribute over 90% of net revenue
3. STRATEGIC INVESTMENT IN LATE-STAGE, PHASE 3 READY ASSETS
Recent approval of Emrosi and strong synergies with Fortress Biotech
Emrosi has potential to exceed annual sales of $200M in the U.S.,
plus additional revenue through global out-licensing opportunities
27 | © 2025 Journey Medical Corporation. All rights reserved.
CORPORATE PRIORITIES AND OBJECTIVES IN 2025
EMROSI launch and TRx demand curve
Progress with payers and ramp up in covered lives with health plan access to EMROSI
Advance business toward sustainable positive EBITDA and profitability
Additional peer-reviewed journal articles and conference posters planned for
EMROSI over the next 12 months
Potential business development transactions including global out-licensing opportunities
Launch of incremental niche dermatology products
NASDAQ: DERM